How To Unlock The Helminth System In Warframe

Key Takeaways

• Customization in Warframe is expanded with the Helminth system, allowing players to add new powers to any Warframe.
• To unlock the Helminth system, players must complete the Earth to Mars Junction, then delve into the Heart of Deimos quest.
• Crafting the Helminth Segment requires specific resources and reaching Associate rank with the Entrati Syndicate.

Customization is a core part of what makes Warframe so enjoyable. Hundreds of mods, cosmetic options, and a near-infinite amount of builds keep players coming back time and time again.

With the Heart of Deimos update, this level of customization was amplified further by allowing players to apply certain Warframe powers onto any Warframe in the game. Players can use Warcry on melee Warframes, Roar to gain a large damage increase, or use Condemn to gain Shields while chaining targets. In order to use these abilities, however, players will need to obtain the Helminth Segment in the Cambion Drift on Deimos. Here is a complete guide on how to unlock the Helminth system in Warframe.

Updated on October 30, 2024, by Rhenn Taguiam: With Warframe: 1999 teasing itself as a thrilling sci-fi prequel story that will explore the world of Warframe before the mysteries of its present-day Origin System, fans of the franchise might be eager to wield more archaic weapons while still enjoy ninja-esque thrills in the upcoming story. However, fans of Warframe who want to start fresh or beginners who are just getting into the game might be intrigued as to just how they can unlock certain aspects of the game, such as the Helminth System. As this part of the RPG takes a few questlines before being fully unlocked, players may be interested in learning just how they can fully access Helminth System, especially in the context of more specific steps in these quests and other requirements.

1 Complete The Earth To Mars Junction

Setup For Tougher Challenges

Before gamers can even start upgrading their Warframes through the Helminth, the game ensures that players are equipped enough to do so. As a majority of the prerequisites for the Helminth are located in Deimos, players need to first access the Red Planet’s moon by unlocking the pathway to Mars. This requires completing the Earth to Mars Junction, which is needed to unlock the “Heart of Deimos” quest.

Requirement: Earth to Mars Junction

As players know in their Warframe gameplay, a Junction is a “bridge” that unlocks the pathway from one planet to another celestial body. In the case of the Earth to Mars Junction, players first need to complete the following:

• Collect 250 Rubedo: This can be done through missions on Earth.
• Complete “Once Awake” Quest: This Main Quest begins as a Grineer Spy Mission in M Prime on Mercury and ends in a Defense mission in Lares on Mercury.

However, before players can even access the Earth to Mars Junction, they need to complete the previous Junctions before it. Their general requirements are the following:

• Venus to Mercury: This requires the defeat of Jackal (Corpus Boss) at Fossa on Venus, a successful extraction after clearing 10 Waves at Tesera on Venus, and completing the “Vox Solaris” Solo Main Quest in Venus.
• Earth to Venus: This requires using Fusion as a means of a Mod rank up, the completion of the “Saya’s Vigil” Solo Main Quest and the “Vor’s Prize” Solo Main Quest.

2 Start The Heart Of Deimos Quest

Introducing The Entreri

When players finish the Earth to Mars Junction, the player will receive a message from Loid. He is a Cephalon servant to the Entrati, a mysterious Orokin family who have taken residence in the Necralisk. Not much is known about them at that time in the player’s experience, but the resulting comments in-game imply they hold some sort of significance to the lore.

Unlocking Heart Of Deimos

The message states that the Entrati have requested the player’s assistance on their home in Cambion Drift, Deimos. Players need to accept this by heading to the Codex on the Orbiter, located directly across from the Marketplace. They can browse the menu untl they see “The Heart of Deimos,” which they can then unlock to formally begin.

3 Reach The Cambion Drift On Deimos

Explore The Brutal Martian Landscape

Players might be surprised to find out that there’s no immediate way of going to the Cambion Drift unless they go to Deimos itself. While there aren’t any Junctions hindering gamers from accessing Deimos from Mars, players do need to explore certain Nodes before unlocking the actual zone.

Within Deimos, players still need to complete specific Nodes to actually unlock the Cambion Drift. These Nodes will give players a general “feel” of the brutal Martian landscape, which, by themselves, are corrupted under Grineer control, with Deimos being an Infested colony.

Unlocking The Cambion Drift

In order to access the Cambion Drift, players need to complete the following Martian Nodes:

• Kadesh (Mars): This is a Defense Mission with a 1,900 + 14,000 Credit Reward that gives access to Deimos.
• Horend (Deimos): A Capture Mission with a 2,100 Credit Reward.
• Phlegyas (Deimos): An Exterminate Mission with a 2,200 Credit Reward.

4 Complete The Heart Of Deimos Quest

Fix The Entrati Family

Players who finally get to the Cambion Drift will find themselves in the company of Loid, from the inbox message, and the Cephalon Otak who happens to share Loid’s body. They explained that the moon’s Infestation is comprised of a unique Grey Stain, which in turn is threatening to corrupt its very Heart. Not much is expounded about the true origins and role of these terminologies – but to avoid spoilers, they become essential components in the game’s later story arcs.

The rest of the quest involves the player meeting every member of the Entrati family, who they eventually realize are the heirs to the Albrecht Entrati’s legacy. As lore fans might remember, Albrecht Entrati is known as the Orokin scientist who was the first to discover the Void and its potential. The rest of the quest goes as follows:

Meet Mother

Before players are able to meet Mother in the Necralisk, they have to prove themselves. Players are instructed to:

• Destroy two (2) Infested Hives.
• The Infested horde has to be destroyed first before the Hive where they came from.

In the Necralisk, Mother explains that the Heart is the power source of the Void, which in turn provides power to Orokin devices. These include Warframes. Players have to stop the Infestation before it corrupts the Heart, or else the Warframes won’t function. Unfortunately, the only person who knows how to help the Heart is Father, who left the Necralisk. Players need to find him.

Find Father

Players venture outside the Necralisk to locate Father. They find a Necramech engaged in battle until its demise. Players eventually find Father in the area, but he doesn’t believe that the Heart is in any danger due to his relationship with Mother. Because of this setback, Loud suggests asking Daughter for help and instructs players to go back to the Necralisk.

Despite this short encounter, players are introduced to the Necramech. This is an Entrati war machine that can be piloted to wreak havoc on the battlefield. In the lore, they were used in the Old War – pertaining to the Orokin’s conflict with the Sentients they created.

Helping Daughter

When players meet Daughter, they are introduced to more of the erratic activities in the Infested landscape of Deimos. Being a family of researchers, it’s no surprise that Daughter is a researcher herself – a biologist, to be exact. She’s only willing to help players if they help rebuild her sample collection in return. Daughter explains that the Cambion Drift occasionally enjoys the presence of two wyrm-like creatures: Fass and Vome. Throughout the day, Vome destroys Fass, which then causes Fass Residue to litter the area. Fass regenerates, the siblings fight, and the cycle continues. Daughter asks the player to:

• Collect 10 Fass Residue.
• They need a Fishing Spear in the Gear before doing so. The locations of the impact sites can create minor HUD distortions.
• Players need at least three (3) Fishes before returning to Daughter. When players use the Residue, they act like Bait and lure fish out. The Fishing Spear cannot penetrate the surface where the fish are; they have to come out of the water first.

When players return to Daughter, she advises them to go to the Heart and speak with Son and to be wary of him.

Meeting Son

When players go outside the Necralisk, they can find an Esophage that should take them to a cave system. In it lies the door to chamber with the Heart and Son, the exiled Entrati who reveals he was the one who released the Grey Stain in a bid to get his family’s attention.

Unlike the other family members, who gave players some fights and gathering missions to complete, finishing Son’s segment to see the Heart requires completing a puzzle:

• The Heart’s door has a Requiem Cipher that has four (4) Requiem Symbols.
• Players need to memorize the Requiem Symbols.
• They have to interact with the Reactive Crystals and repeat the Requiem Symbols pattern from top to bottom.

After unlocking the Chamber, a pulse temporarily disables the Warframe’s combat systems while a Rogue Necramech opens fire to the Heart. With the Heart damaged, players in the Warframe have depleted Shields and can no longer do any special movement. Players are tasked to avoid the Necroamechs and go back to the surface.

Fighting Back

When players return to the surface, the Entrati convene and realize that they must set aside their differences and work together to restore the Heart. Father returns and provides the player with their own Necramech to turn the tide against other Necramechs in the area. Players control this Necramech as they descend and have to do the following:

• Destroy three (3) Infested Hives.
• The Infested horde has to be destroyed before the Hive spawning them can be damaged.
• Players need to interact with special panels to trigger a cutscene of the Heart being healed.
• Players need to defeat the Rogue Necramech (Boss) that open-fired on the Heart from earlier, which is tougher than the others.

Defeating the Rogue Necramech will transfer players back to their Warframe. They have to return to the Necralisk to interact with the family.

Happily Ever After

When players go back to the Necralisk, the Entrati family convenes and introduces Grandmother. She says the Entrati will come together in a crisis despite being a dysfunctional family, with the implication being that she caused the events to happen in the first place.

Rewards

Completing the “Heart of Deimos” Quest provides players with the following:

• Entrati Syndicate
• Bounties (Mother)
• Unique Weapons (Father)
• Fishing (Daughter)
• Wildlife Conversation (Son)
• Mining (Otak)
• Standing Transaction (Grandmother)
• Xaku Blueprint (Warframe)
• Voidrig Blueprint (Necramech)

5 Obtain Standing With Entrati

Curry Favor With The System’s Best Researchers

It’s specifically unlocking the Entrati Syndicate and new interactions with the Entrati family that players need in order to properly unlock the Helminth System. Unlike other Syndicates, the Entrati don’t provide Standing through specific activities. Instead, all activities in the Cambion Drift provide Tokens, which can then be redeemed for Standing.

• Mother Token (1: 100 Standing): From Bounties, which earn the highest when accomplished with Tier 5 runs.
• Father Token (1: 100 Standing): From trading Cambion Drift resources.
• Daughter Token (1: 100 Standing): From trading Fish parts.
• Son Token (1: 100 Standing): From trading Conversation tags.
• Otak Token (1: 100 Standing): From trading Mining resources.
• Grandmother Token (1: 1,500 Standing): From trading other Family Tokens.

6 Reach Associate Rank With The Entrati

A Worthwhile Challenge For The Long-Term Reward

Due to the repetitive nature of some activities in the Cambion Drift, players might feel rather turned off at the notion of even completing them for the Helminth in the first place. However, understanding the overall “cost” of having a better Standing might make the process feel more like a manageable “grand gathering quest.” Here is a list of requirements to achieve Rank 3 with the Entrati:

• 71,000 Standing
• 3 Spinal Core Sections
• 10 Father Tokens
• 10 Daughter Tokens
• 1 Keratinos Gauntlet Blueprint
• 1 Keratinos Blades Blueprint
• 5 Common Avichaea Tag
• 1 Medjay Predasite Tag
• 20 Mother Tokens
• 10 Son Tokens

7 Craft And Install Segment Into Helminth Room

Create The Room

Players now have to create the room for the Helminth itself. To do this, they have to acquire the following prerequisites:

• Entrati Syndicate Rank 3 – Associate
• Master Rank 8
• Helminth Segment: This expands the Helminth Infirmary’s functionalities. Using this upgrade now allows the Helminth to absorb Warframes (Subsume), acquire their powers, and transfer them to another Warframe.
• Helminth Invigoration Segment: This expands the functionalities of the Helminth Infirmary to now provide Warframes with temporary ability boosts.

Helminth Segment

In order to install the Helminth Segment, players need:

• Helminth Segment Blueprint (15,000 Standing)
• 50,000 Credits
• 20 Tempered Bapholite
• 15 Pustulite
• 10 Pustulent Cognitive Nodule
• 5 Vizier Predasite Tag
• 24 Hours

Helminth Invigoration Segment

To install the Helminth Invigoration Segment, players need to:

• Helminth Invigoration Segment Blueprint (30,000 Standing)
• 50,000 Credits
• 50 Thrax Plasm
• 10 Devolved Namalon
• 5 Sporulate Sac
• 2 Entrati Lanthorn
• 24 Hours

8 How To Rank Up Helminth

Improve The Helminth With Upgrades

Helminth is similar to the Focus system in that it has unlocks attached to earning experience with it. While Focus is obtained by earning experience for max rank gear, Helminth is upgraded through resources and interacting with Warframes.

Experience is earned from feeding Helminth materials, subsuming Warframes, and injecting abilities into Warframes. Feeding Helminth is the fastest way of upgrading it for most veteran players with millions of resources, but newer Mastery Rank 8 players can also receive hefty chunks of experience by subsuming Warframes and injecting said abilities into other Warframes. Subsuming a Warframe grants 160,000 experience while injecting an ability grants 80,000.